The All-on-4 concept is a highly successful treatment option for the edentulous patient with excellent clinical outcomes. The All-on-4 concept is a paradigm shift in how implants are placed and angulated compared to traditional concepts with axial placement in a vertical manner. The angulations allow placement that avoids anatomical structures and also allows the use of longer implants, enabling increased bone to implant contact and placement of the implant into better quality bone anteriorly. Placement of dental implants previously in attempts to treat the severely resorbed maxilla and mandible has had only limited success. But the rehabilitation of completely edentulous, atrophied maxilla and mandible by the placement of implants using the AII-on-Four protocol gives new hope for a perceivable success, while becoming a promising treatment method of choice and standard in the care for severely compromised patients.