Patronage studies are an important part of modern Italian Rnaissance art history. This book looks at how and why the Sassetti Chapel in Santa Trinitá was made. What induced the patron to have it decorated, why did he choose the particular church and why as his chosen painter did he choose Domenico Ghirlandaio. The patrons interest in promoting his image both on earth and in heaven are important factors in any Renaissance patronage study none more so given the bitter rivalry for the favour of Lorenzo de Medici between Francesco Sassetti and his banking rival Giovanni Tornabuoni. These two conducted and extensive campaign for the right to have decorated the main chapel in Santa Maria Novella. Sassetti having failed in his bid, not least as he wanted his chapel dedicated to his name saint then had Ghirlandaio create one of the great Florentine fresco cycles.