Excerpt from A Review of the Early Vaccination Controversy: With an Original Letter by Jenner Referring to It, and to the Spread of Vaccination to the Spanish Possessions in America, the Philippines, and Other European Settlements in the Orient<br><br>It will be clear from these statements what a frightfully high mortality attended epidemic small pox, and its prevalence may be estimated from the data presented later by the House of Com mons Committee appointed to investigate cow-pox vaccination. From a calculation made by Dr. Heberden whose name has come down to us through the association with the nodes on the joints in rheumatism, it seems that over a period of thirty years before vaccination 95 persons died of small-pox in London out of every 1000 deaths, and the annual death rate of Great Britain was upward of This would make the number of cases of small-pox annually between based on all the deaths being from the natural disease, to a half million if one-fortieth of the total deaths were due to the inoculated disease.<br><br>About the Publisher<br><br>Forgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.com<br><br>This book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.