This book looks at the histologic outcomes of the commonly seen cryotherapy-ineligible lesions in the Cervical Cancer Prevention Progam in Zambia. The need to know what kind of abnormal cervicography requires to have histologic valuation is vital , particularly in he the low economic situations. Sending all abnormal lesions for histology is costly, leads to over treatment and does not reduce the incidence of cervical cancer. Conversely, using a very stringent criteria to send abnormal lesions for histology may lead to inadvertent missing of cancer cases. An accurate criteria for determining which lesions are cryotherapy-ineligible, and therefore requiring histological examination cannot be overemphasised.