This book is based on the results of a scientific study on the effectiveness of cognitive rehabilitation on cognitive brain functions and quality of life in patients with Multiple Sclerosis(MS).MS is known to be a debilitating disease that, according to statistics, is more prevalent among young people, especially women, who are likely to have different roles in the family and society, including the role of working in the workplace or the important roles of spouse and parent in the family. Because cognitive impairment in these patients affects the quality of life, employment, social life, marriage, and married life, in addition to the patient himself/herself, the quality of life and mental health of other family members, including spouse, children, and even parents are also affected. It is hypothesized that cognitive rehabilitation can slow the progression of defects in cognitive functions in people with MS and prolong the gap between mild cognitive impairment and severe cognitive impairment.