This book provides an in-depth exploration of the theoretical underpinnings of patient safety culture, presents practical methodologies for its enhancement, and offers concrete applications for improving the quality and safety of care. Drawing on extensive research, this book begins by elucidating the fundamental theories underpinning patient safety culture. It examines the relationship between organizational culture, human behavior and patient safety, providing a sound theoretical framework to inform subsequent discussions. The book's application-oriented approach ensures that readers can translate theory and methodology into tangible improvements within healthcare organizations. It features case studies from the Algerian healthcare environment, demonstrating how a strong patient safety culture can lead to a reduction in medical errors, increased staff commitment and improved quality and safety of care.