The present manuscript entitled 'Relative cradle Pathology of Arbuda & Malignancy' comprising a brief introduction to the Arbuda in Ayurvedic and carcinoma in modern parlance. The disease Arbuda and carcinoma is elaborated in detail. The derivation of the word Arbuda which is comprised of two words arbb and vich is dealt. A detailed description of the possible nidana is analysed with an elaborate description regarding Dosha hetu and Vyadhi hetu. An attempt is made to build the probable samprapti in accordance with nidana. Poorvaroopa of the disease is explained. Lakshana are explained in detail. Apart from this, According to Avastha of the disease Lakshana are mentioned with the heading of early, later and terminal stage of Anna and Purish vaha Sroto gata Arbuda. Detailed descriptions of Sadhya- Asadhyata with different Upadrava of Arbuda are explained. Here an attempt is made to understand Gastro intestinal malignancy with that of Arbuda in Udara Pradesh.