These days, consideration on the impact of supply chain strategy on firm performance has dramatically increased. Meanwhile, researchers argue that information system strategy should support the supply chain requirements in order to increase the supply chain performance and firm performance. Each supply chain strategy has certain aim and tries to achieve it.This book attempts to determine which kind of information system strategy could be match in a best manner to meet the supply chain strategy, which is applied. In order to achieve that goal,this book assesses the impact of aligning supply chain strategies with information system strategies on supply chain performance and firm performance. Overall, the results of this study indicate that aligning Supply Chain Management Strategy with Information System Strategy will results in a better supply chain and firm performance.