<p><strong style="color: rgba(0, 0, 0, 1)">Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS) might - at last - have been explained and demystified.&nbsp;</strong></p><p></p><p><span style="color: rgba(0, 0, 0, 1)">Recent research has mapped out the central, interlinking mechanisms which can create an illness of exercise intolerance and post-exertional malaise. Those mechanisms include low blood volume, vascular and cardiac autoimmunity, dysfunctions in the cells and mitochondria, microclots and, in general, a reduction in blood perfusion throughout the body.</span></p><p></p><p><span style="color: rgba(0, 0, 0, 1)">In particular, research from Germany has mapped out a convincing model for how all of these dysfunctions inter-relate and how they are likely part of one big vicious cycle.&nbsp;For the first time, this provides a 'unifying model' of what ME/CFS probably is. Aimed at a patient audience, this book offers accessible explanations of this&nbsp;crucial, breakthrough research&nbsp;by Prof. Klaus Wirth and Prof. Carmen Scheibenbogen.</span></p><p></p><p><span style="color: rgba(0, 0, 0, 1)">This book also focusses on healing strategies and solutions. This includes discussion of various conventional medical procedures and treatments as well as of:</span></p><p></p><p><span style="color: rgba(0, 0, 0, 1)">- the Buteyko method (to improve bodily oxygenation)</span></p><p><span style="color: rgba(0, 0, 0, 1)">- ancestral approaches to nutrition and diet (to improve gut health and energy production)</span></p><p><span style="color: rgba(0, 0, 0, 1)">- the Perrin technique&nbsp;</span></p><p><span style="color: rgba(0, 0, 0, 1)">- treatments for microclots</span></p><p><span style="color: rgba(0, 0, 0, 1)">- the potential strengths - and limitations - of neuroplasticity interventions.</span></p><p></p><p><span style="color: rgba(0, 0, 0, 1)">Possible future medications are also discussed, including the 'Mitodicure' pill. Based on the research of Wirth,&nbsp;this pill could become the world's first ME/CFS-specific medication&nbsp;and one which could be capable of profoundly reducing the suffering of millions worldwide.&nbsp;It could even be a medicine which leads to recovery.</span></p><p></p><p><span style="color: rgba(0, 0, 0, 1)">Patrick Ussher, an ME/CFS patient, weaves together the personal and theoretical in this book, unravelling the most exciting research 'in plain English' but also talking about his own personal experience with various treatments to improve quality of life.&nbsp;He also shares advice on how to construct a life of hope and meaning, despite having a chronic illness.</span></p><p></p><p><span style="color: rgba(0, 0, 0, 1)">This is primarily intended to be a&nbsp;guide and handbook for ME/CFS and Long Covid patients&nbsp;(although it will also likely be of interest to patients with the closely related Fibromyalgia and Postural Orthostatic Tachycardia Syndrome (POTS)).&nbsp;It will help many sufferers understand the true physical nature of their illness and provide them with a range of healing strategies.</span></p><p></p><p><strong style="color: rgba(0, 0, 0, 1)">But most importantly, this is a book which inspires hope for a future in which ME/CFS patients are at last treated with the dignity they deserve and in ways which truly do diminish their suffering.</strong></p><p></p><p><span style="color: rgba(0, 0, 0, 1)">The book has a foreword written by Prof. Klaus Wirth in which he describes his encounter with ME/CFS, subsequent research and initial work on developing the 'Mitodicure' drug.</span></p><p></p><p></p><p></p>