Pharmacovigilance is a science dedicated to monitoring, assessing and evaluating the safety of pharmaceutical products. Despite multiple challenges, this discipline of science has undergone a transformative journey since its inception. This book aims to provide a detail of the current challenges of pharmacovigilance and also throws some light into the current trends and the future offerings shaping its landscape. From its early days as a reactive system to the modern era of proactive surveillance assisted by advanced level of technologies, this book examines key milestones including but not limited to the challenges and emerging opportunities in pharmacovigilance.