<div>This book constitutes the refereed proceedings of the 15th International Conference on Economics of Grids,&nbsp;</div><div>Clouds, Systems, and Services, GECON 2018, held in Pisa, Italy, in September 2018.&nbsp;</div><div>The 21 full papers and 9 short papers presented&nbsp; together with 1 invited talk were carefully&nbsp;reviewed and selected from 40 submissions.</div><div>This GECON 2018 proceedings was structured in three special sessions on selected topics, namely:&nbsp;IT service ecosystems enabled through emerging digital technologies; machine learning, cognitive systems and data&nbsp;science for system management; and blockchain technologies and economics.</div>