This comprehensive guide to medical macroscopy explores a wide range of gynecological pathologies, from myomas to adnexectomies and cystectomies. It also covers specific cases such as the non-tumoral uterus, the particularities of placentas in twin pregnancies, and procedures such as mastectomy, conization and cervico-uterine smear analysis. Each section details in depth the essential protocols for the macroscopic examination of surgical specimens associated with these specific pathologies. This manual is designed to guide healthcare professionals in the careful analysis of specimens, thereby promoting accurate diagnoses and appropriate patient management.