<p>This book constitutes the proceedings of the 23^rd Annual Conference on&nbsp;Research in Computational Molecular Biology, RECOMB 2019, held in Washington, DC, USA, in April 2019.</p>

<p>The 17&nbsp;extended and 20 short abstracts&nbsp;presented were carefully reviewed&nbsp;and selected from 175 submissions. The short abstracts are included in&nbsp;the back matter of the volume. The papers report on original research in all&nbsp;areas of computational molecular biology and bioinformatics.</p>